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Family transmission of hepatitis b virus hbv



Family transmission of hepatitis b virus hbv



Revista Clinica Espanola 182(3): 127-133



We have assessed the prevalence of HBV infection in 449 family members in contact with 126 chronic carriers of HBsAG. More than one third of the relatives had a biological marker indicating positive infection which happens to be HBsAg in 5.79% of them. The comparative results among the different family groups show preferentially a horizontal type of transmission. As well, the prevalence of infection increases in the older group of subjects and in those who have been living with a chronic carrier for a longer time. On the other hand, the existence of HBV markers in family members indicate that genetic factors could play a certain role in the development of a chronic carrier state of hepatitis B virus after first contact with the latter.

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Accession: 005447028

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