Free estrogens and progestogens in benign prostatic hypertrophy

Narayan, J.P.; Srivastava, S.P.; Singh, J.N.

Indian Journal of Physiology and Pharmacology 29(2): 119-122

1985


ISSN/ISBN: 0019-5499
PMID: 2419249
Accession: 005485179

Download citation:  
Text
  |  
BibTeX
  |  
RIS

Article/Abstract emailed within 1 workday
Payments are secure & encrypted
Powered by Stripe
Powered by PayPal

Abstract
Studies on the presence of free estrogens and progestogens in human prostates clearly differentiate the benign hypertrophied prostates from normals. Both contained 17 .alpha.-hydroxypregnenolone 5 .beta.-pregnane-3, 20-dione, 5.alpha.-pregnane-3, 20-dione and 16 .alpha.-hydroxyestrone. However, presence of 11 .alpha.-hydroxyprogesterone 20 .beta.-hydroxypregnenolone, pregnenolone, 17 .alpha.-hydroxyprogesterone, as well as estrone and estriol exclusively in BPH samples pointed to their possible involvement in the development of benign prostate hypertrophy.