Frequencies of hla a hla b hla c and hla bf antigens in schizophrenic patients originated from alsace france

Singer, L.; Mayer, S.; Tongio, M.M.; Roos, M.; Danion, J.M.; Bernard, H.; Leclercq, P.; Hauptmann, G.; Kapfer, M.T.; Bindler, J.; Mandel, P.

Encephale 8(1): 9-15


ISSN/ISBN: 0013-7006
Accession: 005486678

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A comparison of the frequency of HLA-A, -B, -C and -Bf antigens observed in a group of 75 chronic schizophrenics and in a control group of 184, all from Alsace, does not favor a strong genetic association between schizophrenia and the antigens studied. The modifications observed in the schizophrenic sample, i.e., decrease in the frequency of A10 and B5 antigens and increase of A29 and BfF, are not statistically significant when the probabilities are multiplied by the number of tested antigens. The possibility of an association between schizophrenia and the tested antigens should not be excluded.