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Gastric mucin and hydrochloric acid output in gastric aspirates in children after pentagastrin stimulation part 1. in normal gastric acid secretion



Gastric mucin and hydrochloric acid output in gastric aspirates in children after pentagastrin stimulation part 1. in normal gastric acid secretion



Italian Journal of Gastroenterology 20(1): 3-5



HCl and gastric mucin content in the gastric aspirates of 52 children without gastric pathology have been studied in relation to age and body weight. Mucin was estimated by quantitation of its content of galactose and hexosamine. The concentrations and outputs of these two sugars and of HCl were determined in basal conditions and after pentagastrin stimulation. The volume of gastric secretion. HCl concentration and output increase significantly after stimulation, but galactose and hexosamine concentrations decrease, and their outputs after stimulation are variable. The basal concentrations and outputs of galactose and hexosamine do not seem to change in relation to age and weight and HCl stimulates galactose production. The acid/mucin output index decreases after pentagastrin stimulation because of a dilutional effect on galactose and hexosamine.

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Accession: 005505521

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