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Gluco corticoids and mammary gland development mammary cell multiplication and hypertrophy in rabbit



Gluco corticoids and mammary gland development mammary cell multiplication and hypertrophy in rabbit



Annales de Biologie Animale Biochimie Biophysique 18(6): 1325-1332



Previous work demonstrated that glucocorticoids were able to initiate marked multiplication and hypertrophy of the mammary cell during pregnancy in rabbit, essentially when injected from day 19 onwards. In this report, glucocortoid injections during pregnancy induced a drop of progesterone. This effect was not evidenced in early pregnancy, and its intensity increased as pregnancy proceeded. This glucocorticoid action was evidently mediated through a decrease of progesterone.

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