Glycated haemoglobin and glycated plasma protein, a comparative study

Ross, I.S.; Mitchell, A.F.; Stroud, R.E.

Clinica Chimica Acta; International Journal of Clinical Chemistry 156(3): 329-335


ISSN/ISBN: 0009-8981
PMID: 3719989
Accession: 005529625

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Three different analytes reflecting the degree of glycation of different proteins have been used in order to determine which showed best correlation with the glycaemic control of different groups of diabetic patients. 1, Glycated haemoglobin by a semi-automatic colorimetric technique was able to discriminate between the best and worst controlled of the selected diabetic groups; 2, a semi-automated colorimetric glycated plasma protein assay was unable to distinguish between any of the diabetic groups in the study; 3, a dye reducing estimation of glycated plasma protein (Fructosamine) was best able to distinguish between the groups in the study.