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Hemolysis artifacts induced in rotating shear devices



Hemolysis artifacts induced in rotating shear devices



Journal of Biomedical Materials Research 8(1): 81-86



The objectives were to reduce data scatter and to determine whether differences in equipment geometry influenced the disparity of results between various researchers. Shearing tests were repeated, for flat disk and the cone geometries, using a transparent glass bottom to examine the hydrodynamics. Significant differences were seen between the flat disk and cone geometries, the latter being significantly inferior. Human blood under the cone suffered severe air entrainment at speeds above 350 rpm, but under the flat disk entrainment was negligible and interfacial foaming minor even at 520 rpm.

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Accession: 005558338

Download citation: RISBibTeXText

PMID: 4819876

DOI: 10.1002/jbm.820080110


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