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High performance liquid chromatographic determination in human plasma of a anti convulsant benzodiazepine clonazepam



High performance liquid chromatographic determination in human plasma of a anti convulsant benzodiazepine clonazepam



Journal of Liquid Chromatography 6(2): 301-310



A rapid and specific high-pressure liquid chromatographic method for determination of clonazepam in human plasma is described. The analysis is linear for concentrations of 5-100 ng/ml plasma. The method is applicable to quantitation of clonazepam in plasma of subjects receiving 0.05 at 0.20 mg/kg orally, with satisfactory accuracy and precision.

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Accession: 005570944

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