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Hitchhiking effect and linkage dis equilibrium the example of 2 closely linked loci in the pig halothane sensitivity and phospho hexose isomerase



Hitchhiking effect and linkage dis equilibrium the example of 2 closely linked loci in the pig halothane sensitivity and phospho hexose isomerase



Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences Serie D Sciences Naturelles 289(2): 153-156



The observation of 2 lines of pigs selected differently for 4 generations confirms a recent theoretical work (Thomson, 1977) showing that a possible source of linkage disequilibrium may be the hitch-hiking effect of a selected locus (Hal; halothane sensitivity) on another closely linked neutral locus (PHI); phosphohexose isomerase. [Halothane causes malignant hyperthermia in pigs sensitive to this anesthetic. The Hal locus is associated with favorable effects on muscular development].

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Accession: 005581968

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Hitchhiking effect and linkage disequilibrium: the example of two closely linked loci in the swine halothane sensitivity (Hal) and phosphohexose isomerase (PHI). Comptes rendus hebdomadaires des seances Serie D Sciences naturelles, 289(2): 153-156, 1979

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