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Human chorionic gonadotropin 7. preparation and immuno characteristics of carboxyl terminal peptides of the beta subunit of human chorionic gonadotropin

Kawasaki, K.; Iguchi, S.; Kawasaki, C.; Maeda, M.; Okada, Y.; Yamaji, K.; Takagi, T.; Sugita, N.; Tanizawa, O.

Chemical and Pharmaceutical Bulletin (Tokyo) 30(3): 1043-1047

1982


ISSN/ISBN: 0009-2363
Accession: 005591135

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Various carboxyl-terminal peptides of hCG[human chorionic gonadotropin]-.beta. were prepared from the corresponding blocked peptides by trifluoroacetate treatment followed by hydrogenation. The prepared peptides were tested for inhibitory action on the binding between 125I-hCG and the antiserum against the carboxyl-terminal portion of hCG-.beta. An antigenic site of this antiserum may exist around the amino-terminal portion of the carboxyl-terminal hexadecapeptide.

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