Section 6
Chapter 5,592

Human chorionic gonadotropin alpha and human chorionic gonadotropin beta subunits as tumor markers during therapy in a case with so called nonfunctioning islet cell tumor

Oberg, K.; Wide, L.; Bostrom, H.

Acta Medica Scandinavica 210(3): 231-234


ISSN/ISBN: 0001-6101
Accession: 005591137

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A 61-yr-old man with a malignant endocrine pancreatic tumor, so-called non-functioning islet cell tumor, is described. The tumor consisted of enterochromaffin-like cells with positive immunocytochemistry for gastrin, glucagon and VIP [vasoactive intestinal peptide]; neither of these or other peptides were elevated in the circulation. Elevated serum levels of HCG[human chorionic gonadotropin]-.alpha. and HCG-.beta. subunits were found. They seemed to be valuable tumor markers during cytotoxic therapy.

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