+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Immunity to experimental salmonella infection studies of the protective capacity and immunogenicity of lipo poly saccharide acetone killed cells and ribosome rich extracts of salmonella typhimurium in c 3h hej and cd 1 mice

Immunity to experimental salmonella infection studies of the protective capacity and immunogenicity of lipo poly saccharide acetone killed cells and ribosome rich extracts of salmonella typhimurium in c 3h hej and cd 1 mice

Journal of Immunology 121(3): 1010-1014

Phenol-water-extracted lipopolysaccharide [LPS] of S. typhimurium, strain W118-2, was tested for protective capacity and immunogenicity in C3H/HeJ and CD-1 mice 21 days post-vaccination. In C3H/HeJ mice the LPS was not protective and gave no anti-O titer, as measured by passive hemagglutination, whereas in CD-1 mice it was protective and immunogenic. Acetone-killed cells and a ribosomal vaccine prepared from the same strain of Salmonella were protective and resulted in an anti-O titer in the C3H/HeJ and the CD-1 mice. LPS co-extracted with ribosomes, or present in whole cells, is thus more immunogenic for C3H/HeJ mice than phenol-water purified LPS. Ribosome-rich extracts and acetone-killed cells apparently contain substances, in addition to LPS, that modulate the immune response in C3H/HeJ mice. Ribosomal vaccine prepared from a rough strain of S. typhimurium, strain TA1659, that lacks O antigens and makes LPS of the Rc type, did not protect C3H/HeJ or CD-1 mice against Salmonella infection. Mixtures of LPS with ribosomal vaccine derived from this mutant were also tested for their protective capacity. The antigens involved in immunity to Salmonella infection were discussed.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 005622480

Download citation: RISBibTeXText

PMID: 690428

Related references

The protein lipid and carbohydrate composition of protein bodies from lupinus angustifolius cultivar new zealand bitter blue seeds/. Phytochemistry 22(11): 2359-2364, 1983

Comparative efficacy and tolerance of cefamandole and cephalothin as prophylaxis for open heart surgery a randomized double blind study. Journal of Cardiovascular Surgery 23(4): 305-308, 1982

Proteins from ricinus communis seeds iii. isolation and characterization of 2 component polypeptide chains of acid ricin. Khimiya Prirodnykh Soedinenii (6): 887-892, 1987

Studies on hypoglycaemic activity of Solanum xanthocarpum Schrad. & Wendl. fruit extract in rats. Journal of Ethnopharmacology 108(2): 251-256, 2006

Influence of a gene causing hardness on the milling and baking quality of 2 wheats m. Australian Journal of Agricultural Research 20(6): 971-979, 1969

Poly saccharide composition in relation to extensibility and possible peptide linked arabino galactan of lupine hypocotyl cell walls. Phytochemistry (Oxford) 11(5): 1597-1602, 1972

Protective bulk pack container for ice cream cones us patent 4640418. february 3 1987. Official Gazette of the United States Patent and Trademark Office Patents 1075(1): 182, 1987

Protective activity of antigenic preparations isolated by different methods from Streptococcus pneumoniae serotype 3. Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 1981(12): 30-32, 1981

Analysis of immunity to infection with Salmonella typhimurium in outbred mice. I. Requirement of the antibody to non-O antigen for protection in mice that are not protected by the RNA-rich vaccine. Immunology 61(4): 535-541, 1987

Genetic control of susceptibility to mite associated ulcerative dermatitis. Laboratory Animal Science 36(3): 262-267, 1986

Immunity to Salmonella infections. Journal of the South African Veterinary Association 47(2): 89-91, 1976

Osmotic shock a method to eliminate endogenous gamma aminobutyric acid and account for the influence on benzodiazepine binding affinity in autoradiographic studies. Journal of Pharmacology and Experimental Therapeutics 245(1): 342-349, 1988

Detection of immune response against synthetic polymers of amino acids employing the plaque-forming cell system: II. Cross reactions of normal sheep erythrocytes with antibody against glutamic acid, lysine, alanine and tyrosine terpolymers. J Immunol 100(2): 266-273, 1968

Hemopoietic responses in mice injected with purified recombinant murine gm csf. Experimental Hematology (Charlottesville) 15(1): 1-9, 1987

The relative plaque-removing effect of brushes of different length and texture. Dental Practitioner and Dental Record 20(7): 244-248, 1970