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Immunoglobulin e and immunoglobulin g 1 immunoglobulin g 2 and immunoglobulin g 4 in desensitization of pollen asthma



Immunoglobulin e and immunoglobulin g 1 immunoglobulin g 2 and immunoglobulin g 4 in desensitization of pollen asthma



Hawaii Medical Journal 43(11): 410, 412



Parenteral desensitization of asthmatics is time-consuming, often ineffective and occasionally dangerous. The ability to recognize those who will benefit from this therapy would be an advantage. The subclasses of IgG in pollen-sensitive asthmatics were determined by Protein A-Sepharose CL-4B chromatography and Ampholine PAG [polyaerylamide gel] plates during pollen desensitization. Successful desensitization was partially predictable on the pattern of falling IgE and rising IgG blocking antibodies.

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