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Immunoglobulin g immunoglobulin a immunoglobulin m and immunoglobulin e serum levels in asthmatic patients sensitive to house dust and mite allergens after 2 year specific immunotherapy

Immunoglobulin g immunoglobulin a immunoglobulin m and immunoglobulin e serum levels in asthmatic patients sensitive to house dust and mite allergens after 2 year specific immunotherapy

Archivum Immunologiae et Therapiae Experimentalis 32(4): 381-388

Investigations were carried out on 36 atopic asthma patients treated with Allpyral. The serum Ig levels, specific IgE blocking antibodies were determined by various immunological methods. A marked rise in the IgG level appeared after 6 mo. of therapy and maintained during the whole period of observation. This higher IgG level was often correlated with an increase in blocking antibody titer. IgE serum revealed a higher value after 6 months, but on prolongation of the immunotherapy the total IgE level decreased not statistically significantly. The specific IgE antibody showed a tendency to fall after 2-year hyposensitization. The most marked changes in the beahvior of specific IgE and blocking antibodies were observed in the patients with clinical improvement.

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