+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Impaired visual and spatial reversal learning in brain damaged rats additional components of the general learning system of the rodent brain



Impaired visual and spatial reversal learning in brain damaged rats additional components of the general learning system of the rodent brain



Physiological Psychology 10(3): 293-305



The components of the rodent's general learning system (an ensemble of brain structures essential for normal acquisition of a wide variety of laboratory tasks) could roughly be identified by determining which lesion placements within the rat brain would lead to defective acquisition of a spatial discrimination and its reversal as well as a visual discrimination and its reversal. Of the 29 cortical and subcortical sites investigated to date, only 9 qualify as components of the general learning system: pontine reticular formation, mediam raphe, interpeduncular nucleus and central tegmentum, substantia nigra, red nucleus, parafascicular nucleus, lateral thalamus, ventrolateral thalamus and globus pallidus. These 9 brain regions may constitute a major part of an organized nervous substratum mediating anticipatory sets.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 005638567

Download citation: RISBibTeXText

DOI: 10.3758/bf03332953


Related references

Posterolateral hypothalamic and mid brain central gray lesions impair visual and spatial reversal learning further additions to the general learning system of the rodent brain. Physiological Psychology 11(2): 93-102, 1983

Abnormal learning and forgetting of individual spatial reversal problems in brain damaged rats. Physiological Psychology 11(1): 35-46, 1983

Levels of ngf and chat in the central cholinergic system of aged learning impaired rats are resembled by streptozotocin induced damage of brain glucose metabolism and learning abilities in adult rats. Neurobiology of Aging 11(3): 351, 1990

ACTH 4-9 analog can retard spatial alternation learning in brain damaged and normal rats. Behavioral and Neural Biology 52(2): 271-278, 1989

Spatial learning deficits following traumatic brain injury in rats Reversal by bFGF. Japanese Journal of Pharmacology 79(Suppl. 1): 193P, 1998

Successive visual reversal learning in rats as a function of amount of training per reversal and reduced spatial cues. Perceptual and Motor Skills 43(3 Pt 2): 1103-1110, 1976

Reversal learning set in successive discrimination reversal learning and transfer with rats using visual and olfactory cues. Psychological Record 24(2): 243-251, 1974

Rats with low levels of brain docosahexaenoic acid show impaired performance in olfactory-based and spatial learning tasks. Lipids 34 Suppl: S239-S243, 1999

The visual motor and visual perceptual performance of brain damaged children implications for learning. Developmental Medicine & Child Neurology 11(2): 251-252, 1969

Wechsler Memory Scale paired-associate learning in discrimination of brain-damaged and non-brain-damaged psychiatric patients. Perceptual and Motor Skills 39(1): 227-230, 1974

Learning and retentiveness in brain-damaged rats. Journal of Comparative and Physiological Psychology 52: 501-505, 1959

Spatial discrimination reversal learning in weanling rats is impaired by striatal administration of an NMDA-receptor antagonist. Learning and Memory 16(9): 564-572, 2009

RNA metabolism in regions of mouse brain during spatial reversal learning. Physiology and Behavior 14(3): 239-243, 1975

The effect of frustration and reduced spatial cues on visual discrimination and reversal learning in rats. Australian Journal of Psychology 25(3): 233-241, 1973

Effects of perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on spatial and visual reversal learning in rats. Neurotoxicology & Teratology 25(4): 459-471, July-August, 2003