Section 6
Chapter 5,655

In vivo enamel fluoride uptake from and caries inhibition by topical fluoride agents

Gibbs, M.; Retief, D.H.; Bradley, E.L.; Taylor, R.E.; Walker, A.R.

Journal of Dental Research 60(4): 770-775


ISSN/ISBN: 0022-0345
PMID: 6937513
DOI: 10.1177/00220345810600040101
Accession: 005654465

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Acidulated phosphate fluoride (APF), Duraphat or Fluor Protector, was applied to the molar teeth of rats fed a cariogenic diet. The first maxillary molar teeth were subjected to a microbiopsy procedure for fluoride analysis and the mandibular molars scored for caries. All three topical fluoride agents produced a significant increase in the fluoride content of the outermost 5.0 micron of enamel. Only APF produced a significant reduction in caries incidence at all sites.

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