Induction of urinary bladder epithelial tumors in rats with n 4 5 nitro 2 furyl 2 thiazolyl formamide

Vlasov, N.N.; Pliss, G.B.; Balin, V.V.

Voprosy Onkologii (St Petersburg) 26(3): 63-67


ISSN/ISBN: 0507-3758
Accession: 005675700

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Of 20 white non-inbred rats fed through lifetime N-4-(5-nitro-2-furyl)- 2-thiazolylformamide (concentration, 0.188%), transition cell vesical tumors developed in 4 animals between the 56th and 70th wk. After 71-81 wk cancer of this organ developed in the remaining animals. The maximum total dose of the carcinogen was 14.4 g/rat. The maximum observation terms was 567 days.