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Industrial styrene poisoning 13. experimental studies on damage to the mucosal membrane of respiratory tracts of rats exposed to styrene contemporary observations of changes in ciliary functions and fine structure



Industrial styrene poisoning 13. experimental studies on damage to the mucosal membrane of respiratory tracts of rats exposed to styrene contemporary observations of changes in ciliary functions and fine structure



Japanese Journal of Industrial Health 24(4): 360-372



Styrene has an irritating effect on the tracheal mucosa, but there are few reports that have demonstrated it histologically. Styrene exposure experiments were carried out on rats and observations were made on morphological changes of the trachea with EM. Observations on its functional aspects were made by estimation of the cilliary movement per minute. A considerable damaging effect of styrene on the tracheal mucosa was revealed which could be used as an index in setting the maximum permissible concentration of styrene for the future.

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