Influence of duration of fixation on the yield of chromosome aberrations in human lymphocyte culture exposed to gamma radiation at different mitotic cycle stages/

Sevan'kaev B.A.B.; Lychev, V.A.

Radiobiologiya 23(4): 471-475

1983


Accession: 005683859

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Abstract
A comparative study was made of the yield of chromosome aberrations in human lymphocyte culture exposed to 60Co-.gamma.-rays (2 Gy ) at different mitotic cycle stages, the cells being fixed after 52 and 60 h. With the latter fixation time, frequency of chromosome aberrations after irradiation in G1 stage was substantially lower than that with the former one (52 h) and, vice-versa, it was higher after irradiation in S and G2 stages. Probable causes of the distinctions are discussed.