Kinetic determination of serum hapto globin in patients with hemolytic anemia

Abdalla, D.S.P.; Hoxter, G.

Revista de Farmacia e Bioquimica da Universidade de Sao Paulo 18(2): 127-143


ISSN/ISBN: 0370-4726
Accession: 005780693

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A kinetic method for serum haptoglobin determination was evaluated in 101 normal persons and 20 patients with hemolytic anemia. The kinetic method has shown good accuracy, precision and sensitivity for use in laboratory routine. The mean haptoglobin serum levels of the hemolytic anemia group were lower (P < 0.001) than those of the control group. A statistically significant correlation was found between haptoglobin, reticulocyte count and total number of erythrocytes in the hematolytic anemia group.