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Labetalol in controlled hypotension: administration of labetalol when adequate hypotension is difficult to achieve

Labetalol in controlled hypotension: administration of labetalol when adequate hypotension is difficult to achieve

British Journal of Anaesthesia 51(4): 359-365

A study of controlled hypotension was undertaken in 50 major surgical patients using labetalol, a drug with both alpha- and beta-adrenoceptor blocking activity. The patients were such that difficulty in achieving controlled hypotension could be anticipated: the young, the anxious and those for whom halothane was contraindicated. The administration of labetalol quickly induced hypotension which was controlled easily and was rapidly antagonized.

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Accession: 005787151

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PMID: 465259

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