+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Labile metabolites and phosphorylase a in rapidly frozen rat cerebral cortex

Labile metabolites and phosphorylase a in rapidly frozen rat cerebral cortex

Journal of Neurochemistry 30(2): 493-496

The influence of freezing speed was evaluated by analyses of phosphocreatine (PCr), ATP, ADP, AMP, cyclic AMP and phosphorylase a activity in cerebral cortex of lightly anesthetized rats. The freezing speed did not influence cerebral energy state. The somewhat lower ATP concentration observed in animals frozen through the dura was unassociated with increases in ADP or AMP (the size of the adenine nucleotide pool was lower). The results confirmed previous ones in showing that freezing of brain cortex through intact skull bone or exposed dura gives high values for PCr and ATP, and low values for ADP and AMP.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 005787204

Download citation: RISBibTeXText

PMID: 624954

DOI: 10.1111/j.1471-4159.1978.tb06555.x

Related references

Phosphorylase alpha and labile metabolites during anoxia: correlation to membrane fluxes of K+ and Ca2+. Journal of Neurochemistry 55(5): 1690-1696, 1990

Cytoplasmic filaments at the presynaptic active zone in rapidly frozen cerebellar cortex. Society for Neuroscience Abstracts 10(1): 545, 1984

Binding of tritiated l glutamate to fresh or frozen synaptic membrane and postsynaptic density fractions isolated from cerebral cortex and cerebellum of fresh or frozen canine brain. Journal of Neurochemistry 46(3): 831-841, 1986

The presence of biologically labile compounds during ischemia and their relationship to the EEG in rat cerebral cortex and hypothalamus. Journal of Neurochemistry 19(12): 2843-2853, 1972

Quantitative scanning transmission electron microscopy of ultrathin cryosections: subcellular organelles in rapidly frozen liver and cerebellar cortex. Journal of Structural Biology 110(3): 244-255, 1993

Organization of the mouse cerebral cortex a histochemical study using glycogen phosphorylase. Brain Research 267(2): 201-216, 1983

Cerebral cortex responds rapidly to thyroid hormones. Science 214(4520): 571-573, 1981

Changes of cyclic AMP and phosphorylase a in mouse cerebral cortex during seizures induced by 3-mercaptopropionic acid. Brain Research 135(2): 337-346, 1977

The presence of biologically labile compounds during ischemia and their relationship to the electro encephalogram in rat cerebral cortex and hypothalamus. Journal Of Neurochemistry: 2843-2853, 1972

Kainic acid rapidly induces cyclooxygenase (COX)-2 in piglet cerebral cortex. Neuroreport 11(16): 3435-3438, 2000

Glycogen phosphorylase activity in the cerebral cortex of rats during development: Effect of homocysteine-induced seizures. Brain Research 694(1-2): 128-132, 1995

Continuous venovenous hemofiltration rapidly lowers toxic metabolites in a patient with MSUD and imminent cerebral herniation. Klinische Padiatrie 222(4): 264-265, 2010

The cholinergic innervation develops early and rapidly in the rat cerebral cortex: A quantitative immunocytochemical study. Neuroscience 108(4): 555-567, 18 December, 2001

Amyloid precursor protein in the cerebral cortex is rapidly and persistently induced by loss of subcortical innervation. Proceedings of the National Academy of Sciences of the United States of America 90(18): 8712-8716, 1993

Experimental study of the blood-brain barrier in the frozen cerebral cortex. European Neurology 3(5): 293-302, 1970