Lability of high density lipo protein cholesterol during serum storage
Lability of high density lipo protein cholesterol during serum storage
Curb, J.D.; Overturf, M.L.; Harrist, R.B.
Atherosclerosis 37(4): 641-646
1980
In many clinical and research situations it would be desirable to store, for extended periods, specimens on which measurements of high density lipoprotein cholesterol (HDL-C) levels were desired. To test the effects of storage on subsequent HDL-C levels, divided serum specimens from 46 subjects were frozen at -80.degree. C and analyzed at intervals throughout a 12 mo. period. A statistically significant increase in the HDL-C levels was found (P < 0.01). Caution must be exercised in interpreting the results of HDL-C analysis done on specimens stored for prolonged periods at -80.degree. C.