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Laboratory diagnosis of tuberculous lymph adenitis using soluble antigen fluorescent antibody test



Laboratory diagnosis of tuberculous lymph adenitis using soluble antigen fluorescent antibody test



Indian Journal of Medical Research 76(JULY): 1-4



A total of 136 patients 1 mo.-12 yr old with chronic enlarged lymph nodes were examined from Jan. 1978-Aug. 1979 for tuberculous etiology. Detailed clinical history and laboratory investigations, including histopathological and microbiological examination of lymph nodes were carried out. Presence of antitubercular antibodies was studied using the modified soluble antigen fluorescent antibody (SAFA) test. The mantoux test was also carried out in all these cases. It was difficult to demonstrate mycobacteria in lymph nodes. SAFA test using mycobacterial saline extract antigen appears to be a more useful serological test in establishing the diagnosis of tuberculous lymphadenopathy, especially when the histopathological picture is non-specific.

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Accession: 005787684

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PMID: 6816726


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