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Laboratory evaluation of 3 novel insecticides inhibiting cuticle formation against some susceptible and resistant stored products beetles



Laboratory evaluation of 3 novel insecticides inhibiting cuticle formation against some susceptible and resistant stored products beetles



Journal of Stored Products Research 11(3-4): 187-193



The insecticidal activity of three 1-(2,6-disubstituted-benzoyl)-3-phenylureas was evaluated against a number of susceptible and resistant stored products beetles. The compounds were DU 19111 [1-(2,6-dichlorobenzoyl)-3-(3,4-dichlorophenyl)-urea], PH60-38 [1-(2,6-dichlorobenzoly)- 3-(4-chlorophenyl)-urea] and PH60-40 [1-(4-chlorophenyl)-3-(2,6-difluorobenzoyl)-urea]. PH60-40 was the most effective compound against susceptible strains of Sitophilus granarius, S. oryzae, Tribolium castaneum and Lasioderma serricorne. All 3 compounds were ineffective against Stegobium paniceum. A strain of T. castaneum (Kuala Lumpur strain) showing malathion-specific resistance was more susceptible to PH60-40 than its "susceptible" strain. A non-specific resistant strain of T. castaneum (CTC12 strain) showed approximately twice the tolerance to PH60-40 compared with the "susceptible" strain. PH60-40 had ovicidal properties and also killed young larvae of T. castaneum after short exposure periods. Oviposition was not affected. Wheat sprayed with an emulsifiable formulation of PH60-40 at 2, 5 or 10 ppm was protected against susceptible T. castaneum, S. granarius and Oryzaephilus surinamensis and against resistant S. oryzae and T. castaneum (Kuala Lumpur strain) following 40 wk storage at 20.degree. C and 44 wk storage at 35.degree. C. Preliminary toxicological data indicates that PH60-40 is of a sufficient order of safety for consideration of grain admixture. The compound is therefore of potential interest as a replacement for the more conventional grain protectants especially in situations where resistance is producing increasing control problems.

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Accession: 005787712

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