+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Lebers optic neuropathy 2. fluorescein angiographic studies



Lebers optic neuropathy 2. fluorescein angiographic studies



Documenta Ophthalmologica 53(2): 113-122



Fluorescein angiography was performed in 71 persons at risk to develop Leber's Optic Neuropathy (LON), in 10 female carriers of this disease and in 5 patients during the acute phase. The examination was performed in 3 university eye clinics. The angiograms were randomly mixed with an equal number of controls and reviewed in a blind fashion on 2 occasions by 2 observers. A scoring system was developed on the basis of the peripapillary microvascular changes known to occur in the acute phase of LON. All 5 patients could be recognized in this manner. In the pictures of one of the clinics, which were of good quality, a significant difference in scoring between the at risk and control groups appeared to exist. Carriers also may have the same fluorescein angiographic abnormalities. One man from the at risk group who obtained high abnormal scores, identical to patients in the acute phase, developed LON 6 mo. later.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 005800134

Download citation: RISBibTeXText

PMID: 7173013


Related references

Fluorescein angiographic abnormalities in lebers optic neuropathy. Ophthalmologica 185(2): 98, 1982

Fluorescein angiographic characteristics of the optic disc in ischemic and glaucomatous optic neuropathy. Current Opinion in Ophthalmology 6(2): 30-35, 1995

Fluorescein angiographic findings in optic disks with dysthyroid optic neuropathy. Folia Ophthalmologica Japonica 41(6): 1243-1250, 1990

Fluorescein angiographic findings in optic discs with dysthyroid optic neuropathy. Orbit 10(2): 89-96, 1991

Fluorescein angiographic findings regarding the optic disc in cases of low-tension glaucoma and the chronic stage of anterior ischemic optic neuropathy. Nippon Ganka Gakkai Zasshi 97(10): 1225-1230, 1993

Lebers optic neuropathy 1. clinical studies. Documenta Ophthalmologica 53(2): 97-112, 1982

Prevalence of mtDNA mutations associated with Lebers hereditary optic neuropathy in familial MS and MS patients with prominent optic neuropathy. Neurology 50(4 Suppl. 4): A149, 1998

Two secondary Lebers hereditary optic neuropathy mutations found in a family with maternal inherited multisystem disorder lacking optic neuropathy. Modern Pathology 17(2): 270, 2004

Fluorescein angiographic features of choroidal insufficiency in anterior ischemic optic neuropathy. Korean Journal of Ophthalmology 13(2): 100-104, 1999

Electro physiological and clinical studies in lebers hereditary optic neuropathy. Clinical Research 25(2): 131A, 1977

Histologic and morphometric comparisons of human optic nerves Congenital Optic Nerve hypoplasia versus Lebers hereditary optic neuropathy. Investigative Ophthalmology & Visual Science 38(4 Part 1-2): S389, 1997

Nonarteritic anterior ischemic optic neuropathy with macular edema: visual improvement and fluorescein angiographic characteristics. Journal of Neuro-Ophthalmology 18(3): 166-168, 1998

Risk factors, clinical findings, and fluorescein angiographic features in patients with anterior ischemic optic neuropathy (AION). Ophthalmologe 93(4): 354-360, 1996

Pathogenetic aspects of the glaucomatous optic neuropathy: fluorescein angiographic findings in patients with primary open angle glaucoma. Brain Research Bulletin 62(6): 517-524, 2004

Lebers hereditary optic neuropathy Mitochondrial mutations and optic nerve degeneration. Investigative Ophthalmology & Visual Science 37(3): S922, 1996