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Long term intra muscular triamcinolone acetonide therapy in alopecia areata alopecia totalis and alopecia universalis



Long term intra muscular triamcinolone acetonide therapy in alopecia areata alopecia totalis and alopecia universalis



Archiv fuer Dermatologische Forschung 261(1): 73-76



Eleven cases of alopecia areata totalis and universalis treated by parenteral administration of triamcinolone-acetonide were investigated. The complete regrowth of hair was noted in 3 patients. Five patients had patchy alopecia areata after therapy. One patient with alopecia totalis and 2 with alopecia universalis showed no favorable effects. In 8 patients regrowth of hair was seen. After discontinuation of therapy, the longest time of maintaining hair regrowth lasted from 4-9 wk, average 6 wk. There were no significant differences in the number of dystrophic anagen hairs and the number of the telogen hairs before and after treatment. This means, that despite of the sometimes complete regrowth the hair root pattern did not improve. Discontinuation of therapy caused rapid loss of hair. Long-term treatment was accompanied by a partial regrowth in 5 cases and by the complete regrowth in 3 cases. After discontinuation of treatment the hair continued to grow for an average of 6 wk, the longest time was 9 wk.

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Accession: 005829362

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