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Metabolism of galactosylceramide in the twitcher mouse an animal model of human globoid cell leukodystrophy



Metabolism of galactosylceramide in the twitcher mouse an animal model of human globoid cell leukodystrophy



Biochimica et Biophysica Acta 879(2): 215-220



The metabolism of galactosylceramide was investigated in normal and twitcher mice, an animal model for human globoid cell leukodystrophy. The findings were compared with data obtained on human tissues. In vitro studies demonstrated that there were two genetically distinct enzymes that hydrolyze galactosylceramide: galactosylceramidase I and II.

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Accession: 005884071

Download citation: RISBibTeXText

PMID: 3094585

DOI: 10.1016/0005-2760(86)90105-0



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