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Multi channel spectral electro encephalogram analysis of caffeine effects



Multi channel spectral electro encephalogram analysis of caffeine effects



Zeitschrift fuer Ernaehrungswissenschaft 15(1): 71-79



Using multichannel EEG spectral analysis central effects of caffeine were investigated during a controlled factorial study with 9 male volunteers. The effects of coffee and caffeine solution with equal concentration, decaffeinated coffee and hot H2O were compared on the basis of analysis of variance. The factorial experimental design implemented a randomization concerning the sequence of substances and days of the week. Coffee and caffeine solution of equal concentration cannot be readily distinguished in their EEG effects; decaffeinated coffee and hot H2O exhibit very similar EEG effects. Very marked differences were found between the 2 groups of substances. Coffee and caffeine solution both produce a remarkable, highly significant reduction of .theta.-amplitude, dominant .theta.-frequency and .theta.-frequency-variation. The alterations within the .alpha.-range are mainly an increase of dominant frequency and a decrease of amplitude, possible signs of remarkable activation and elevation of vigilance. EEG effects of caffeine, and those of other compounds with central effects, are characterized by topographically different effects. These are quantitative and partially qualitative differences.

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