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Natural killer cyto toxicity of human lymphocytes in vitro 1. cyto toxicity enhanced by ok 432 picibanil against a human skin cancer cell line



Natural killer cyto toxicity of human lymphocytes in vitro 1. cyto toxicity enhanced by ok 432 picibanil against a human skin cancer cell line



Journal of Dermatology (Tokyo) 10(6): 519-524



The cytotoxicity of allogenic human lymphocytes was measured by 51Cr release from the target cells (HSC-1). The null cell fraction as well as the T cell fraction treated with anti-T cell monoclonal antibody showed cytotoxicity against the target cells; this was not enhanced by the addition of monocytes. Apparently, the observed killing was natural killer-like cytotoxicity. Enhancement of cytotoxicity was observed when OK-432 was present in the culture of lymphocytes.

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Accession: 005959081

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