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Neural regulation of duodenal alkali secretion: effects of electrical field stimulation

Neural regulation of duodenal alkali secretion: effects of electrical field stimulation

American Journal of Physiology 254(2 Pt 1): G162-G167

The role of transmitters released from enteric neurons in regulating bicarbonate secretion by the proximal duodenum has been studied using electrical field stimulation (EFS). Stripped duodenal mucosa from Rana catesbeiana was mounted as an intact tube over circular platinum electrodes, and luminal alkalinization was measured by pH stat titration before, during, and after EFS. Transmucosal potential difference (PD) was simultaneously measured before and after EFS by paired electrodes.

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Accession: 005966749

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PMID: 3126666

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