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Neutralization kinetic analysis of echovirus 30 and coxsackievirus b 4 strains revealed little antigenic variation among the echovirus strains

Neutralization kinetic analysis of echovirus 30 and coxsackievirus b 4 strains revealed little antigenic variation among the echovirus strains

Australian Journal of Experimental Biology and Medical Science 63(2): 219-222

An antigenic analysis was made of echovirus 30 and coxsackievirus B4 isolates by determining neutralization rate constants in neutralization kinetic tests. The 7 echovirus 30 isolates included the prototype strain and 6 others isolated in Melbourne, Australia, between 1959-1982. Little antigenic heterogeneity was observed in contrast to the evidence of antigenic variation recorded in similar tests on 7 coxsackievirus B4 isolates. These isolates also included the prototype strain, as well as 6 others isolated in Melbourne between 1958-1973. The results obtained with the coxsackievirus B4 isolates were keeping with those observed particularly with the polioviruses and also coxsackievirus B4 by other workers. Those obtained with the echovirus 30 isolates were unexpected, as this virus is also a member of the enterovirus group.

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Accession: 005972258

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PMID: 2994613

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