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Ola major histo compatibility complex of sheep frequency of factors in sheep affected by scrapie or healthy sheep



Ola major histo compatibility complex of sheep frequency of factors in sheep affected by scrapie or healthy sheep



Comptes Rendus des Seances de l'Academie des Sciences Serie III Sciences de la Vie 294(2): 87-90



The OLA histocompatibility complex of sheep was studied in a flock of Ile-de-France breed affected with scrapie. Gene frequencies of 9 of 11 factors were increased in the non-affected sheep of this contaminated flock. In these sheep, frequencies of the 3 following genes appeared to be increased significantly: OLA-A4, OLA-A8, OLA-B6. When these genes were present in the sheep of this flock, the relative risk of scrapie was estimated at 0.05, 0.10 and 0.25, respectively.

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Accession: 006021326

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