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On the influence of carrageenan galactose and 2 4 dinitrophenol on the phagocytosis of staphylococcus aureus and escherichia coli by polymorphonuclear leukocytes



On the influence of carrageenan galactose and 2 4 dinitrophenol on the phagocytosis of staphylococcus aureus and escherichia coli by polymorphonuclear leukocytes



Allergie und Immunologie (Leipzig) 30(4): 212-221



The influence of carrageenan (0.1, 0.05 and 0.01%), galactose (1 .times. 10-1, 1 .times. 10-2 and 5 .times. 10-2 mol/l) and 2,4-dinitrophenol (5 .times. 10-4, 1 .times. 10-4, 5 .times. 10-5 and 1 .times. 10-5 mol/l) on the phagocytosis of S. aureus SG 511 and E. coli 04/K31 by polymorphonuclear neutrophil granulocytes was studied. The capacity of the bacteria to grow and multiply in presence of different concentrations of the analyzed compounds was tested. The phagocytosis of S. aureus SG 511 was not inhibited by carrageenan, galactose and 2,4-dinitrophenyl, but an influence on the phagocytosis of E. coli 04/K31 could be clearly demonstrated (0.1 and 0.005% carrageenan, 1 .times. 10-1 mol/l galactose, 5 .times. 10-4 and 1 .times. 10-4 mol/l 2,4-dinitrophenol). The multiplication of staphylococci and E. coli was not influenced by all 3 compounds.

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