On the possible interaction of caffeine with the fragmented sarcoplasmic reticulum of rabbit skeletal muscle
Bong-Ha, D.; Kim, H.D.
Korean Journal of Zoology 19(4): 161-170
1976
Accession: 006030094
The action of caffeine on the fragmented sarcoplasmic reticulum of rabbit skeletal muscle was studied. Caffeine seemed not to bind tightly to the sarcoplasmic reticulum. The determination of sulfhydryl content of the fragmented sarcoplasmic reticulum, however, suggested that caffeine in some unknown manner influences the protein moiety and thereby increases the sulfhydryl content. The inhibition of Ca uptake by caffeine therefore might be considered as due to the result of this change in protein sulfhydryl content.