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Panendoscopy and renal transplant. Endoscopic and histologic findings

Panendoscopy and renal transplant. Endoscopic and histologic findings

Revista Espanola de Las Enfermedades del Aparato Digestivo 69(5): 453-456

As a consequence of gastroduodenal complications, 20 receptors of primary renal transplants from cadavers (12 males and 8 females) were studied. Patient characteristics were: useful function (creatinine < 2 mg/100 ml.), minimal digestive symptomatology, aged 21 to 48 years, all under immunosuppression with prednisone + azathioprine, and a mean transplant time of 33 months. Panendoscopy was realized and the gastric body and antrum and duodenum were biopsied; X-ray films were made of esophagus, estomach and duodenum and stool was examined in F2Am for occult blood. The radiology only showed changes in the duodenal miter in 3 cases. Stool study was always negative, but in every patient endoscopy revealed lesions that were corroborated by biopsy and classified as: superficial chronic gastritis (7 cases), erosive gastritis (5 cases), superficial chronic duodenitis (5 cases), chronic gastritis + duodenal ulcer (1 case) and chronic gastritis + erosive duodenitis (1 case) and chronic gastroduodenitis (1 case). In patients with signs of duodenal inflammation, Giardia lamblia was found in smears taken under endoscopic control, significantly different (p < 0.05) from the control group. The good tolerance and absence of complications with the method used, together with the excellent endoscopic-biopsy correspondence in comparison with the poor radiologic results obtained, justify the proposal that panendoscopy is useful and recommendabel for early detection of gastroduodenal lesions in renal transplant receptors, in whom these alterations have serious implications.

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Accession: 006059693

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PMID: 3526444

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