EurekaMag
+ Translate
+ Most Popular
Gaucher's disease;thirty-two years experience at Siriraj Hospital
A study of Macrobathra Meyrick from China (Lepidoptera, Cosmopterigidae)
First occurrence in ores of tetragonal chalcocite
Effects of trace element nutrition on sleep patterns in adult women
N.Z. range management guidelines. 2. Design of grazing management systems for tussock country
A case of lipoma of the esophagus
A revision of world Acanthosomatidae (Heteroptera: Pentatomidae): keys to and descriptions of subfamilies, tribes and genera, with designation of types
Life history of the coronate scyphozoan Linuche unguiculata (Swartz, 1788)
Perceptual restoration of obliterated sounds
Mutagenicity studies on two chromium(III) coordination compounds
The formation of the skeleton. I. Growth of a long bone. 1st appearance of a center of calcification
Leucopenia and abnormal liver function in travellers on malaria chemoprophylaxis
The joint commission: four key root causes loom large in sentinel event data
Treatment of vitiligo with topical 15% lactic acid solution in combination with ultra violet-A
Behaviour of dairy cows within three hours after feed supply: I. Influence of housing type and time elapsing after feed supply
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Management and control of patients with type 2 diabetes mellitus in Lebanon: results from the International Diabetes Management Practices Study (IDMPS)
The diet composition and nutritional knowledge of patients with anorexia nervosa
Physoporella croatica Herak, 1958 of the Slovak karst Anisian (Slovakia, the West Carpathians Mts.)
Bright lights, big noise. How effective are vehicle warning systems?
Ein Plesiosaurier-Rest mit Magensteinen aus mittlerem Lias von Quedlinburg
Incidence of Chlamydia trachomatis in patients with sterility
Monster soup: the microscope and Victorian fantasy
Preliminary tests with residual sprays against poultry lice
Duration of the life of plants in phylogeny

Pathological features of experimental gonococcal infection in mice and guinea pigs


Pathological features of experimental gonococcal infection in mice and guinea pigs



Infection and Immunity 13(3): 909-914



ISSN/ISBN: 0019-9567

PMID: 818019

The histopathological and immunofluorescent findings in tissues within and surrounding artificially created subcutaneous tissue cavities infected with Neisseria gonorrhoeae for 1 to 30 days were studied in mice and guinea pigs. Findings in the tissue cavities of the animal models were similar to the findings of disseminated gonococcal infection in humans. These similarities included an intense persistent polymorphonuclear leukocytic response with tissue necrosis, hemorrhage into the early lesion, a perivascular leukocytic response in adjacent tissue, difficulty in detecting large numbers of discrete morphologically typical gonococci by the tissue Gram stain and direct fluorescent antibody techniques, a decrease in the number of identifiable gonococci with duration of the infection, and moderate amounts of extracellular and intracellular immunofluorescent gonococcal debris. Studies into the pathogenesis of the animal infections may enhance our understanding of the pathogenic mechanism (s) associated with gonococcal infection in humans.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 006072079

Download citation: RISBibTeXText

Related references

Features of the formation of antibodies to heterologous antigens in experimental Shigella infection in guinea pigs and mice. Mikrobiologicheskii Zhurnal 51(3): 52-56, 1989

Pathological and biochemical features of Legionella pneumophila infection in guinea-pigs. Journal of Medical Microbiology 15(3): 317-326, 1982

Pathogenesis of experimental Trichophyton infection in guinea-pigs. I. Clinical and pathological findings in primary infection. Arch. exp. VetMed 20: 979-1004, 1966

Pathological changes caused by experimental trypanosomiasis in mice, rats, and guinea-pigs. Trudy Uzbekskogo Nauchno issledovatel' skogo Veterinarnogo Institut 20: 70-72, 1972

Experimental Junin virus infection of guinea pigs. I. Pathological anatomy. Medicina 36(3): 197-206, 1976

Experimental Vibrio fetus infection in guinea pigs. II. Pathological aspects. American Journal of Veterinary Research 15(54): 137-139, 1954

Pathological findings of experimental Toxoplasma gondii infection in guinea pigs. Etlik Veteriner Mikrobiyoloji Dergisi 12(1/2): 23-38, 2001

Pathological changes in guinea-pigs and their aborted foetuses in experimental 'neorickettsial' infection. Veterinarnomeditisinski Nauki, Sofia 10(6): 57-66, 1973

Pathological observations in experimental candida infection of sensitized guinea pigs. Mycopathologia 91(3): 187-192, 1985

Pathological findings of experimental Candida albicans infection in guinea pigs. Ankara Universitesi Veteriner Fakultesi Dergisi 51(2): 133-142, 2004

Pathological observations in experimental candida infection of sensitized guinea pigs. Mycopathologia (1975) 91(3): 187-192, 1985

Pathological features of experimental infection with Eperythrozoon suis in pigs. Taiwan Journal of Veterinary Medicine and Animal Husbandry 58: 27-32, 1991

Haematological and pathological responses to experimental Trixacarus caviae infection in guinea pigs. Journal of Comparative Pathology 104(2): 179-185, 1991

Studies on the influence of BCG inoculation to experimental tuberculous guinea pigs. Report. 1. The relation between the tuberculin skin reaction and pathological changes in experimental tuberculous guinea pigs. Nagasaki Med Jour 34(6): 674-680, 1959

On the pathogenesis of experimental trichophytosis of guinea pigs. 1. Clinical and pathological anatomic studies during primary infection. Archiv für Experimentelle Veterinarmedizin 20(5): 979-1004, 1966