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Penstemonoside and other iridoids from castilleja rhexifolia conversion of penstemonoside to the pyridine monoterpene alkaloid rhexifoline






Journal of Natural Products (Lloydia) 47(5): 854-857

Penstemonoside and other iridoids from castilleja rhexifolia conversion of penstemonoside to the pyridine monoterpene alkaloid rhexifoline

Blossom heads of C. rhexifolia yielded the iridiod glucosides penstemonoside, catalpol and aucubin in approximately equal amounts. Penstemonoside was converted to its aglycone with .beta.-glucosidase, and the aglycone was transformed into the pyridine monoterpene alkaloid rhexifoline by treatment with NH3. The conversion of penstemonoside into rhexifoline corroborates the rhexifoline structure proposed from spectroscopic data and also establishes its absolute stereochemistry.

Accession: 006079068

DOI: 10.1021/np50035a017

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Related references

Stermitz, F.; Harris, G.; Jing, W., 1986: Iridoids and alkaloids from Castilleja host plants for Platyptilia pica. Rhexifoline content of P. pica. Iridoid and alkaloid analyses were conducted on Castilleja sulphurea, C. occidentalis, C. rhexifolia and C. hispida (Scrophulariaceae). Pyrrolizidine alkaloids were found in C. rhexifolia and some C. sulphurea populations, but other C. sulphurea p...

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