+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Pentobarbital treatment of refractory status epilepticus

Neurology 37(3): 500-503

Pentobarbital treatment of refractory status epilepticus

We studied nine patients with status epilepticus refractory to standard therapy. In all patients so treated, IV pentobarbital terminated seizure activity. Mortality was high (77%) in those treated, but was attributed to underlying pathology and possibly to duration of status epilepticus. Pentobarbital therapy should be initiated within 0 to 2 hours after onset of seizures, with continuous EEG monitoring in an intensive care unit.

(PDF 0-2 workdays service: $29.90)

Accession: 006079295

PMID: 3822147

Related references

Pentobarbital in the treatment of status epilepticus refractory to benzodiazepines and phenytoin. Epilepsia 29(5): 689-690, 1988

Incidence and management of hypotension in pentobarbital treatment for refractory status epilepticus. Journal of the Neurological Sciences 150(SUPPL ): S98, 1997

Pentobarbital and EEG burst suppression in treatment of status epilepticus refractory to benzodiazepines and phenytoin. Epilepsia 31(1): 61-67, 1990

Treatment of refractory status epilepticus with pentobarbital, propofol, or midazolam: A systematic review. Epilepsia 43(2): 146-153, February, 2002

Is pentobarbital safe and efficacious in the treatment of super-refractory status epilepticus: a cohort study. Critical Care 18(3): R103-R103, 2015

High-dose pentobarbital treatment of refractory status epilepticus A meta-analysis of published studies. Epilepsia 33(SUPPL 3): 5, 1992

Treatment of refractory generalized tonic-clonic status epilepticus with pentobarbital anesthesia after high-dose phenytoin. Epilepsia 30(4): 464-471, 1989

Pentobarbital in refractory status epilepticus. Pediatric Pharmacology 3(2): 63-67, 1983

Midazolam and pentobarbital for refractory status epilepticus. Pediatric Neurology 20(4): 259-264, 1999

Prolonged convulsive status epilepticus refractory to pentobarbital. Epilepsia 30(5): 638-639, 1989