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Pentobarbital treatment of refractory status epilepticus

Pentobarbital treatment of refractory status epilepticus

Neurology 37(3): 500-503

We studied nine patients with status epilepticus refractory to standard therapy. In all patients so treated, IV pentobarbital terminated seizure activity. Mortality was high (77%) in those treated, but was attributed to underlying pathology and possibly to duration of status epilepticus. Pentobarbital therapy should be initiated within 0 to 2 hours after onset of seizures, with continuous EEG monitoring in an intensive care unit.

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Accession: 006079295

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PMID: 3822147

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