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Peptide synthesis 3. comparative solid phase syntheses of human beta endorphin on poly amide supports using tert butoxycarbonyl and fluorenylemthoxycarbonyl protecting groups



Peptide synthesis 3. comparative solid phase syntheses of human beta endorphin on poly amide supports using tert butoxycarbonyl and fluorenylemthoxycarbonyl protecting groups



Journal of the Chemical Society Perkin Transactions I (1): 65-74



Solid-phase syntheses of the 31 residue peptide human .beta.-endorphin on polar polyamide supports are described. Minimization of acidic reaction conditions by replacement of the customary t-butoxycarbonyl and benzyl-based protecting groups by fluorenylmethoxycarbonyl and t-butyl gave a higher yield of purer product.

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Accession: 006079924

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