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Pharmaceutical analysis using micellar electrokinetic capillary chromatography


Journal of Chromatographic Science 26(8): 406-409
Pharmaceutical analysis using micellar electrokinetic capillary chromatography
The potential utility in pharmaceutical analysis of a capillary electrokinetic separation technique that employs a micellar "pseudo-stationary phase" is discussed and illustrated. Chromatograms of separations of vitamin metabolites and derivatized amino acids are presented to illustrate the high efficiency of the technique and the ability to simultaneously separate of the technique and the ability to simultaneously separate that charged and neutral components of pharmaceutical samples. The analytical characteristics of the technique and the importance of optimizing experimental parameters, such as surfactant concentration and capillary column diameter, are discussed and demonstrated with the aid of chromatograms.

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Accession: 006092965

PMID: 3215989

DOI: 10.1093/chromsci/26.8.406



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