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Plasmodium chabaudi infection of mice effects of chloroquine and mefloquine inhibition of ornithine decarboxylase ec 4.1.1.17 activity



Plasmodium chabaudi infection of mice effects of chloroquine and mefloquine inhibition of ornithine decarboxylase ec 4.1.1.17 activity



Tropenmedizin und Parasitologie 32(2): 73-76



Ornithine decarboxylase activity was inhibited in P. chabaudi-infected red cells of mice treated with chloroquine, mefloquine, primaquine and floxacrine. In vitro experiments on membrane-bound enzymes performed with intact P. chabaudi-infected red cells and corresponding ghost preparations showed a stimulation of Na+K+-ATPase and Ca2+Mg2+-ATPase activity in the presence of chloroquine, mefloquine and floxacrine.

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Accession: 006133145

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