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Platelet adhesion to smooth and rough hydrophobic and hydrophilic surfaces under conditions of static exposure and laminar flow



Platelet adhesion to smooth and rough hydrophobic and hydrophilic surfaces under conditions of static exposure and laminar flow



Biomaterials 2(3): 156-158



Platelet adhesion was measured on well-defined smooth surfaces and on the same surfaces with a known amount of roughness, under static conditions and in a new flow cell producing laminar flow. The pig platelet suspensions show that under static conditions surface roughness does not influence platelet adhesion. With the flow cell an effect of roughness could be demonstrated, both with pig platelet suspension and with fresh canine blood; platelet adhesion decreased on a rough hydrophilic surface (glass) when compared with the same smooth surface, and increased on a rough hydrophilic surface (glass) when compared with the same smooth surface, and increased on a rough hydrophobic surface (silane) when compared with the same smooth surface at the flow rates studied.

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Accession: 006133920

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PMID: 7272405



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