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Platelets and arachidonic acid metabolism in human and experimental hypercholesterolemia



Platelets and arachidonic acid metabolism in human and experimental hypercholesterolemia



Vasa. Zeitschrift für Gefasskrankheiten 13(4): 333-337



Platelets may be determining factors in the occurrence of the thromboembolic complications and in the development of atherosclerosis in hypercholesterolemia. Such disease, however, are multifactorial and platelets may directly or via their released products modulate the behavior of other cell systems, such as leukocytes, endothelial and smooth muscle cells. In particular studies on platelet-vessels wall interactions in different vascular beds, such as coronary and cerebral district, will contribute to the understanding of the basic mechanisms of platelet activation in the atherosclerotic disease.

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Accession: 006135264

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PMID: 6440376



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