+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Post tetanic potentiation and inhibition in single fibers isolated from frog rana pipiens semitendinosus muscle

Post tetanic potentiation and inhibition in single fibers isolated from frog rana pipiens semitendinosus muscle

Japanese Journal of Physiology 32(1): 103-120

The twitch contractions of single fibers from the frog semitendinosus, innervated and denervated, were studied consecutively over a brief period (2-3 s) of conditioning stimulation (CS), at frequencies varying from 1-120/s. Twitch potentiation was consistently observed in denervated fibers at all rates of CS used. Maximal potentiation was attained within the first 12 s after the end of CS, which then decayed progressively. The overall duration of the effect was longer than 5 min. The time course of potentiated twitches was slightly shortened. Inhibition preceding potentiation was the prevailing effect on innervated fibers under the present conditions. Inhibition appeared either after a short interval (.ltoreq. 500 ms) between the end of CS and the beginning of the subsequent twitch, or after several repetitions of the conditioning schedule. The latter form of inhibition was replaced by potentiation when the corresponding fibers were allowed to rest for 60 min before further conditioning stimulations. Maximal inhibition was attained shortly after the end of CS, which then progressively disappeared. On occasion, inhibition lasted longer than 5 min. The time course of inhibited twitches was slightly enlarged. After fatigue, CS produced twitch inhibition on innervated fibers. In denervated muscles the effect was either potentiation or inhibition.

(PDF 0-2 workdays service: $29.90)

Accession: 006153390

Download citation: RISBibTeXText

Related references

Post-tetanic potentiation and inhibition in single fibres isolated from frog semitendinosus muscle. Japanese Journal of Physiology 32(1): 103-119, 1982

Prolonged post tetanic de polarization of frog rana pipiens dorsal root fibers. Neuroscience 9(1): 235-243, 1983

Localization of ph regulating transport systems to the surface membrane of semitendinosus muscle isolated from the frog rana pipiens. Journal of Physiology (Cambridge) 427: 56P, 1990

Post tetanic stiffness in isolated frog muscle fibers. Acta Physiologica Scandinavica 109(3): 30A, 1980

Transverse impedance of single frog rana pipiens skeletal muscle fibers. Biophysical Journal 40(1): 51-60, 1982

Static tension and post tetanic potentiation in activated single fibres from frog muscle. Biophysical Journal 82(1 Part 2): 368a-369a, January, 2002

Liposomes effect of temperature on their mode of action on single frog rana pipiens skeletal muscle fibers. Biochimica Et Biophysica Acta: 427-432, 1980

Effects of excitation contraction uncoupling by stretch and hypertonicity on metabolism and tension in single frog rana pipiens muscle fibers. Journal of General Physiology 80(1): 73-82, 1982

Post freeze survival and muscle function in the leopard frog rana pipiens and the wood frog rana sylvatica. Journal of Thermal Biology 17(2): 121-124, 1992

The effect of K+ on the recovery of the twitch and tetanic force following fatigue in the sartorius muscle of the frog, Rana pipiens. Journal of Muscle Research & Cell Motility 15(4): 420-431, 1994

De nervated muscle rate of propagation and effects of manganese ions and glycerol on the fibrillatory activity of frog rana pipiens semitendinosus. Japanese Journal of Physiology 29(6): 723-738, 1979