+ Translate

Preparation of enantiomeric erythro and threo 1 2 3 pentanetriols by an enzymatic racemate resolution

, : Preparation of enantiomeric erythro and threo 1 2 3 pentanetriols by an enzymatic racemate resolution. Liebigs Annalen der Chemie (7): 629-632

(2R,3S)- and (2S,3R)-erythro- (9a/9b) as well as (2R,3R)- and (2S,3S)-threo-1,2,3-pentanetriol (10a/10b) are synthesized from the rac. trans- and cis-isomeric 2,3-epoxypentyl butyrates 5/6 by Lipase-controlled racemate resolution followed by regioselective ring opening of both the chiral epoxy alcohols 3a/3b and 4a/4b, respectively. Whereas the erythro-triols 9a and 9b are obtained in very good enantiomeric excesses, the reaction sequence yields poor ee values in the case of the threo-triols 10a and 10b.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 006173076

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Takaki M.; Neya T.; Nakayama S., 1983: Role and localization of a region in the pons which has a descending inhibitory influence on sympathetically mediated inhibition of the recto rectal reflex of guinea pigs. The site of origin and the possible function of a supraspinal descending-inhibitory influence over the lumbar sympathetic component of the recto-rectal reflex of guinea pigs were studied. The recto-rectal reflex contraction was not changed by supr...

Lacasse, Lynn; Lum, Cheemun, 2004: Wernicke encephalopathy in a patient with T-cell leukemia and severe malnutrition. Canadian Journal of Neurological Sciences 31(1): 97-98

Skodol, Andrew, E.; Oldham, John, M.; Bender, Donna, S.; Dyck, Ingrid, R.; Stout, Robert, L.; Morey, Leslie, C.; Shea, M. Tracie; Zanarini, Mary, C.; Sanislow, Charles, A.; Grilo, Carlos, M.; Mcglashan, Thomas, H.; Gunderson, John, G., 2005: Dimensional representations of DSM-IV personality disorders: Relationships to functional impairment. Objective: This study compared three-dimensional representations of DSM-IV personality disorders and standard categories with respect to their associations with psychosocial functioning.Method: Six hundred sixty-eight patients with semistructured...

Chen, Ting; Jaffe, Jacob, D.; Church, George, M., 2001: Algorithms for identifying protein cross-links via tandem mass spectrometry. Cross-linking technology combined with tandem mass spectrometry (MS-MS) is a powerful method that provides a rapid solution to the discovery of protein-protein interactions and protein structures. We studied the problem of detecting cross-linked p...

White, Christopher J., 1994: Wiktor coronary stent. Cardiology Clinics 12(4): 665-671

Ejsmont Karabin, J., 1998: Abundance and structure of rotifer community in a humic Lake Smolak twenty years after the experimental mineral fertilisation. Liming and supplying with N, P and K of a humic Lake Smolak carried out in 1971-1974 resulted in changes of abundance and composition of the rotifer community. The changes indicated eutrophication of the lake. Discontinuation of treatment caused f...

Claudia Rutte; Michael Taborsky, 2008: The influence of social experience on cooperative behaviour of rats (Rattus norvegicus): direct vs generalised reciprocity. Cooperation among non-kin has been attributed sometimes to reciprocal altruism: Two or more individuals exchange behaviour that benefits the respective partner. According to direct reciprocity, cooperation is based on past behaviour of a known par...

Ventura F.; Figueras A.; Caixach J.; Fraisse D.; Rivera J., 1989: Fab mass spectrometry of sulfonated dyes application to water analysis. Several commercial dyes (nitro, azo, disazo, trisazo, oxazine and antrhraquinone) ranging from mono to trisulphonated compounds were analyzed by fast atom bombardment (FAB) mass spectrometry. Glycerol and dithiothreitol + dithioerythritol (5:1) ga...

Hann, S. K.; Kim, J. B.; Im, S.; Han, K. H.; Park, Y. K., 1993: Itraconazole-induced acute hepatitis. A case is reported in a 51-yr-old woman from Korea with fungal toenail onycholysis and subungual hyperkeratosis, who was treated with oral itraconazole (100 mg/d). After 116 d of therapy, the patient developed nausea and jaundice and treatment was...

Bugarcic, Z.; Susic, S.; okic, A., 1991: Research on Dutch potato cultivars in the agroecological conditions of Kaona and Golija. In 1988-90 twelve potato cultivars were tested at Kaona (600 m alt.) and Golija (1600 m alt.), Yugoslavia. There were significant differences in yield between sites for all cultivars. Good adaptability and satisfactory yields at both sites were sh...