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Preparation of fluorine 18 labelled n fluoropyridinium triflate


, : Preparation of fluorine 18 labelled n fluoropyridinium triflate. Journal of Labelled Compounds & Radiopharmaceuticals 35(9): 999-1006

N-Fluoropyridinium triflate was labelled with 18F proceeding through N-trimethylsilylpyridinium triflate and [18F]F2 diluted to 1% in Ne. A typical experiment afforded this new fluorine-18 transfer reagent with up to 46% radiochemical yield. The specific activity of 18F-labeled N-fluoropyridinium triflate was determined by iodometric titration to be in the range of 4 .cntdot. 10-8 mg/Bq (1.5 mg/mCi; 1.67 .cntdot. 10-4 Ci/.mu.M).

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