+ Translate

Preparation of kaurenolide and its 5 alpha 6 alpha h isomer

, : Preparation of kaurenolide and its 5 alpha 6 alpha h isomer. Journal of the Chemical Society Perkin Transactions I (2): 517-520

In the preparation of kaurenolide [a fungal metabolite], essentially by the literature method, the formation of ent-6-oxokaur-16-en-19-oic acid from the toluene-p-sulfonate of 7.beta.-hydroxykaurenolide was dependent on the quality of the lithium iodide monohydrate used. ent-6-Hydroxykaura-6,16-dien-19-oic acid 19,6-lactone, prepared from the toluene-p-sulfonate of 7.beta.-hydroxykaurenolide, zinc dust and sodium iodide in refluxing 2-methoxyethanol, was hydrolyzed by base to ent-6-oxo-5.beta.-kaur-16-en-19-oic acid, which gave the 5.alpha.,6.alpha.(H) isomer of kaurenolide upon reduction.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 006173379

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Gedney L.; Van Wormer J., 1973: Tectonic mapping in Alaska with ERTS-1 imagery. Faults, fracture patterns, infrared surveys.

Heese, H. D. V.; Freeseman, Christine, 1964: Determination of mixed venous PCO2 in infants and children. The present study confirms the simplicity and reliability of the rebreathing method for the estimation of the mixed venous PCO2 in apnoeic children of all ages. The application of the method permits the control of alveolar ventilation within physi...

Florez, A.; Malpartida, E.; Bryant, F. C.; Wiggers, E. P., 1983: Nutrient content and phenology of cool-season grasses of Peru. Changes in CP concn. and in vitro DM digestibility (IVDMD) associated with phenological development were documented for the cool-season grasses Calamagrostis vicunarum, Festuca rigescens, F. dolichophylla, Muhlenbergia ligularis, M. peruviana, Sti...

Johnson, D. A.; Redmer, D. A.; Reynolds, L. P., 1994: Histological evaluation of cell proliferation in the uterus of intact and steroid-treated ovariectomized ewes. Journal of Animal Science 72(SUPPL 2): 74

Yuemei Cui; Xijun Chang; Xiangbing Zhu; Haixia Luo; Zheng Hu; Xiaojun Zou; Qun He, 2007: Chemically modified silica gel with p-dimethylaminobenzaldehyde for selective solid-phase extraction and preconcentration of Cr(III), Cu(II), Ni(II), Pb(II) and Zn(II) by ICP-OES. Silica gel-bound amines phase modified with p-dimethylaminobenzaldehyde (p-DMABD) was prepared based on chemical immobilization technique. The product (SG-p-DMABD) was used as an adsorbent for the solid-phase extraction (SPE) Cr(III), Cu(II), Ni(I...

Alaoua, M. D.; Alam, M.; Khaja, F.; Rybicki, B.; Goldstein, S.; Sabbah, H.; Smith, S.; Wulbrecht, N.; Richer Cornish, K.; Borzak, S., 1998: The ECG has limited value for detecting left atrial enlargement. Journal of the American College of Cardiology 31(2 SUPPL A): 446A, Feb

Broka , V. S.; Neengevich, M. R., 1941: The distribution of Mytilaster lineatus in the Caspian Sea. M. lineatus, having been accidentally introduced into the Caspian Sea from the Black Sea around 1920, has subsequently spread widely by natural processes and by accidental distribution. At the time of this article the authors considered it the lea...

Ledezma D., 1984: Measurements of free calcium in human malignant hyper thermic muscles. Biophysical Journalpart 2: 48a

Saad, Adib; Billard, Roland, 1995: Production and management of spermatozoa in the European catfish Silurus glanis. Aquatic Living Resources 8(4): 323-328

Aguilera-Romero, Auxiliadora; Kaminska, Joanna; Spang, Anne; Riezman, Howard; Muniz, Manuel, 2007: The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus. The p24 family members are transmembrane proteins assembled into heteromeric complexes that continuously cycle between the ER and the Golgi apparatus. These cargo proteins were assumed to play a structural role in COPI budding because of their ma...