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Preparation of r ibuprofen and related carboxylic acids using microbial oxidation of an aromatic hydrocarbon by rhodococcus sp bpm 1613

Preparation of r ibuprofen and related carboxylic acids using microbial oxidation of an aromatic hydrocarbon by rhodococcus sp bpm 1613

Agricultural & Biological Chemistry 48(10): 2501-2504

(R)-2-(4'-Isobutylphenyl)propanoic acid (ibuprofen), (S)-3-(4'-isobutylphenyl)butanoic acid and (S)-4-(4'-isobutylphenyl)pentanoic acid were obtained using microbial oxidation of (.+-.)-1-isobuty-4-(1'-methyloctyl)benzene by Rhodococcus sp. BPM 1613.

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Accession: 006173756

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DOI: 10.1080/00021369.1984.10866522

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