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Preparation of Rocky Mountain spotted fever vaccine suitable for human immunization

, : Preparation of Rocky Mountain spotted fever vaccine suitable for human immunization. Journal of Clinical Microbiology 1(6): 500-503

Rocky Mountain spotted fever vaccine was produced from rickettsiae grown in chicken embryo cells in roller bottle cultures. The rickettsiae were concentrated and purified by passage through a sucrose gradient and inactivated with formalin. This vaccine satisfactorily passed preinactivation and final container testing and is believed to be superior to the presently available yolk sac vaccine.

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Accession: 006173829

PMID: 809483

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